CAS Number: 960129-66-2Molecular Weight: 660Salt Form: TFAPurity: >95%Sequence (3-letter): Asn-Asn-Trp-Asn-Asn-OHSequence (1-letter): NNWNN-OHStorage: -20 °C or below

Extracellular death factor (EDF) is a linear pentapeptide that activates the cell death pathway in a subset of communicating cells. Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. It is sensitive to extreme pH, high temperatures, and other cellular stress. EDF has been shown to trigger cell death at 2.5 ng/ml which significantly reduces population size in some E. coli cultures.

References

Belitsky M, Avshalom H, Erental A, Yelin I, Kumar S, London N, Sperber M, Schueler-Furman O, Engelberg-Kulka H (2011) “The Escherichia coli Extracellular Death Factor EDF Induces the Endoribonucleolytic Activities of the Toxins MazF and ChpBK” Mol. Cell 41 (6) 625-635

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。