Molecular Weight: 681.31Salt Form: AcetatePurity: >96%Sequence (3-letter): Boc-Val-Pro-Arg-AFCSequence (1-letter): Boc-VPR-AFCStorage: -20 °C or below

Boc-Val-Pro-Arg-AMC is a fluorogenic substrate for alpha-thrombin (Km = 21 μM, k_cat = 109 s^-1) and the thrombin-staphylocoagulase complex (Km = 25 μM, k_cat = 89 s^-1). The substrate is also cleaved by trypsin, tryptase from rat mast cells, Kex2 endoprotease, and acrosin and spermosin (trypsin-like enzymes from sperm of the ascidian Halocynthia roretzi).

Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。