CAS Number: 17650-98-5Molecular Weight: 1351.44Salt Form: N/APurity: >96%Sequence (3-letter): Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2Sequence (1-letter): (Glp)QD(Tyr(SO3H))TGWMDF-NH2Storage: -20 °C or belowSolubility: water, >1 mg/mL

Caerulein is a sulfated peptide that is used in the study of NF-κB-mediated signaling. When administered via i.v., it can produce analgesia. It has also been shown to induce pancreatitis in animals at high doses and prevent pain associated with gall-bladder contraction and intermittent claudication.

Glp = Pyroglutamic acid

References

1. Baber, N.S., Dourish, C.T. and Hill, D.R. (1989) “The role of CCK, caerulein, and CCK antagonists in nociception” Pain 9: 307-328.2.Watanabe, O. et al (1984) “Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis” Am. J. Physiol. 246(4 Pt 1): G457-67.

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。