Recombinant full-length human Sphingosine kinase 1 with N-terminal 6xHis tag

Storage: Store product > -70 ºC. Enzyme is stable for at least 6 months at -70 ºC as undiluted stockGenBank Accession number: AF200328Molecular Weight: 46.9 kDa

Sphingosine kinase 1  (SphK1) is a lipid kinase responsible for the formation of Sphingosine 1-phosphate (S1P) from sphingosine. SphK1 is found in the cytosol of eukaryotic cells until activated and it migrates to the plasma membrane. There are two isoforms of SphK; SphK1 and SphK2. Both isoforms are available from Echelon.

This recombinant full-length human Sphingosine kinase 1 with N-terminal 6xHis tag is tested for activity against sphingosine. It is expressed in a baculovirus infected Sf9 insect cell expression system.

Keywords: Sphingosine kinase, SPHK, SK, Sphingosine kinase-1, SPHK1 enzyme, SK1

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Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。