Molecular Weight: 1359.65Salt Form: TFAPurity: >96%Sequence (3-letter): Ala-Leu-Glu-Arg-Thr-Phe-Phe(NO2)-Ser-Phe-Pro-Thr-OHSequence (1-letter): ALERTFF(NO2)SFPT-OHStorage: -20 °C or below

Plasmepsin II is an aspartic acid protease produced by plasmodium parasites and related to human β-secretases. Plasmepsin II activity can be detected by the synthetic substrate ALERTFF(NO2)SFPT-OH through cleavage of the Phe-Phe(NO2) bond. The substrate cleavage re-action is monitored by the decrease in the average absorbance from 284 –324 nm.

Reference: Protein Science (1999), 8: 2001–2009.

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。