Phosphatidylinositol diC4 (PI diC4) is a synthetic, purified dibutanoyl PI.

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

Alternate Names: Dibutanoyl Phosphatidylinositol, PtdIns C4, PI C4, (4:0/4:0) PI

Bulk discounts available, please email echelon@echelon-inc.com for information.

Publications

Powered by Bioz See more details on Bioz

1) Guo, J., M. R. Wenk, et al. (2003). “Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles.” Proc Natl Acad Sci U S A 100(7): 3995-4000.2) He, F., M. Mao, et al. (2004). “Enhancement of phototransduction g protein-effector interactions by phosphoinositides.” J Biol Chem 279(10): 8986-90.3) Kobayashi, M., R. K. Mutharasan, et al. (2004). “Identification of hydrophobic interactions between proteins and lipids: free fatty acids activate phospholipase C delta1 via allosterism.” Biochemistry 43(23): 7522-33.

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。