Truncated sphingosine-1-phosphate lyase (a.a. 62-5686) with N-terminal His tag

Storage: Store product < -70 ºC. Enzyme is stable for at least 6 months at -70 ºC as undiluted stockSpecific Activity: request Certificate of Analysis (COA)

Product Description

This truncated sphingosine 1-phosphate lyase (a.a. 62-5686) protein has a N-terminal His tag, was expressed in Sf9 cells, and was purified using nickel-NTA chromatrography. Activity was verified using a modified version of the S1P ELISA kit. See below for the protocol TDS. Please request the certificate of analysis to see the specific activity of our current lot.

Sphingosine-1-phosphate lyase (SPL) (E.C.4.1.2.27) works as a key regulator in the final step of the sphingolipid degradative pathway by irreversibly breaking down sphingosine-1-phosphate (S1P) to ethanolamine phosphate and hexadecenal. S1P signaling, through its five receptors, is involved in many biological events such as proliferation, inflammation, and apoptosis in cancer and other degenerative diseases.

Echelon-脂类研究的最佳拍档

Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。