![]() ![]() | CatalogNo.: K-5400 Description: Echelon’sPI(5)P4-KinaseActivityAssayisanATPdepletionassaywhichquantifiestheremainingATPlevelsinsolutionfollowingthekinasereaction.TheassaycanbeusedtoquantifyPI(5)P4-Kinaseinvitroorincelllysate. | ||
TypeIIPI(5)P4-Kinase(PIP4KII)catalyzesthephosphorylationofphosphatidylinositol-5-phosphate[PI(5)P]tophosphatidylinositol-4,5-bisphosphate[PI(4,5)P2].PIP4KIIhasbeenshowntoplayaroleincertaintypesofbreastandcoloncancerinadditiontobeingimportantinseveralphysiologicalprocessessuchasinsulinsignaling,stressresponse,andembryonicdevelopmentinseveralmodelorganisms.IthasalsobeenimplicatedasanimportantregulatorofnuclearPI(5)Plevels. Storage-20°CRelatedProducts:Substrates:P-5016,P-5008RelatedEnzymes:PI3Kα(E-2000),PTEN(E-3000),SHIP2(E-1000) RelatedAssays:PI(4)P5-Kinase(PIP4KI)ActivityAssay(K-5700),PI3-KinaseActivityELISA(K-1000s),PTENActivityELISA(K-4700) 品牌介绍
Echelon-脂类研究的最佳拍档 Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病,例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息,脂质信号分析的顶级供应商。 |