CatalogNo.: K-6000 Description: Echelon’sHyaluronidaseActivityELISAisaquantitativeimmunoassaydesignedforinvitromeasurementofhyaluronidaseactivityinBIOLOGicalsamples. | |||
HyaluronidasesareagroupofenzymesthatdegradeHyaluronan(HA),alinearpolysaccharidecomprisedofarepeatingdisaccharideofN-acetylglucosamineandD-glucuronicacid.HAisinvolvedinmanybiologicalprocessesincludingstructuralsupport,cellmigrationandtissueturnover.CirculatingHAlevelshavealsobeenshowntocorrelateinseveraldisorderssuchasliverdiseaseandcertaintypesofcancer.HyaluronidaseshavebecomeanimportantareaofstudyduetotheirregulatoryfunctioninHAmetabolismandtheirroleinphysiologicalprocessessuchasfertilizationandwoundhealing.ElevatedexpressionlevelsofthegeneencodingHyaluronidase1havebeenfoundinatypicalductalhyperplastictissues,suggestingthepossibilitythatitmaybeaviablebioMarkerforidentifyingpremalignantlesionsthatcandevelopintobreastcancer.Researchhasalsoshownthathyaluronidasesareinvolvedinseveralpathologicalprocessessuchasbacterialpathogenesis,thespreADIngoftoxins/venomsandcancerprogression,makinghyaluronidasesapotentialpharmacologicaltarget. StoragePart1at-20°CandPart2at4°CRelatedProducts:HAELISA(K-1200),HASandwichELISA(K-4800),CollagenIVELISAKit(K-1700). ProductKeywords:Hyaluronan,Hyaluronate,LiverCirrhosis,RheumatoidArthritis,Osteoarthritis,LiverFibrosis |
Echelon-脂类研究的最佳拍档
Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病,例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息,脂质信号分析的顶级供应商。