 | CatalogNo.: K-1700s Description: TheCollagenIVELISAKitIIisasandwichELISAforthequantificationofsolublehumanCollagenIV. AssayRange:3.1-200ng/mLCollagenIV SampleVolume:20μL/sampleforresultsinduplicate | ||
Productbackground:CollagenIVisamajorcomponentoftheextracellularmatrixandprovidesthemainstructuralsupportforthebasementmembrane.IthasbeendemonstratedthatavarietyofdiseasescausealterationsinCollagenIVsynthesis,degradationandreleaseatthetissuelevel.TheserumlevelofCollagenIVisalteredinseveraltypesofdiseases,includingliverfibrosis(agoodindexwithhyaluronicacid)andcirhosis.ResearchhasshownthatthelossofCollagenIVinthebasementmembrane(withaconcurrentincreaseinCollagenaseactivity)positivelycorrelateswiththeprogressionofcancer.CollagenIVintheseramaybeindicativeoftissueCollagenIVdegradationandmaycorrelatewithcancerprogression. | |||
Echelon-脂类研究的最佳拍档
Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。
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