 | CatalogNo.: K-3900s Description: Echelon'sCMLELISAKitIIisasecondgenerationcompetitiveimmunoassaydesignedforinvitromeasurementofCMLlevelsinBIOLOGicalsamples. AssayRange:3,000-4.0ng/mL Samplevolume:40μL/sample AssayIncubationTime:2hr | ||
ProductBackground:CarboxymethylLysine(CML)isanadvancedglycationendproduct(AGE)formedbyoxidativestressandglycosylation.AGE's,includingCML,canaccumulateintissuescausinginflammation.ExcessiveAGE'salsoreduceantioxidantdefense,weakenimmunesystems,impairDNArepairmechanisms,andpromotetheaccumulationoftoxinsandinfectionsintissues.CMLadductshavebeenfoundtoaccumulateinmanydiseasesincludingAlzheimersdisease,diabetes,chronicobstructivepulmonarydisease(COPD),acceleratedperiodontaldisease,renaldisease,andatherosclerosis. | |||
Echelon-脂类研究的最佳拍档
Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病，例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息，脂质信号分析的顶级供应商。
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