CatalogNo.: T-1900 Description: TheS1PassayservicesusestheS1PELISAkit(K-1900)toquantifyLPAinBIOLOGicalsamples(96-wellformat).Sphingosine1Phosphate(S1P)isakeycomponentofthesphingolipidsignalingcascade.S1Pinitiatesaproliferative,pro-angiogenic,andanti-apoptoticsequenceofeventscontributingtocancerprogression.RecentresearchhassuggestedthatS1PisapotenttumOrigenicgrowthfactorthatislikelyreleasedfromtumorcellsandthatS1PmaybeanovelbioMarkerforearlystagecancerdetection.Sphingosinekinasehasalsobeenshowntobeup-regulatedinavarietyofcancertypes(S1Pisproducedviatheactivityofsphingosinekinasephosphorylatingsphingosine).TheEchelonS1PAssayisasensitiveandrobustmethodforthequantificationofS1Pinbiologicalsamples. | |||
Disclaimer:TheS1PAssayServicewasco-developedusingaproprietarymonoclonalantibodyfromLpathInc.(SanDiego,CA).Lpath,Inc.hasanumberofpatentapplicationspendingorissuedcoveringmaterial(s)incorporatedintothisassay.Theassay’ssolepermitteduseisfornon-clinicalresearchtomeasureS1Pinbiologicalsamples.Anyotheruse,includingdrugdiscovery,requiresalicensefromLpath.(www.lpath.com). |
Echelon-脂类研究的最佳拍档
Echelon是脂质研究和脂质与蛋白质相互作用研究领域的引导者。脂质蛋白相互作用是众多的细胞信号通路钟高级调控必不可少的。异常的细胞信号通路将会导致许多疾病,例如癌症、炎症、糖尿病和心血管疾病等。Echelon一直是脂质研究信息,脂质信号分析的顶级供应商。